Spreading the word real quick about a program I have quickly grown to love. www.clipstudio.net/en Clip Studio! It combines everything I love about Manga Studio (paneling, text, text bubbles, tones, perspective rulers, manga effects, useful full-color brushes) with everything I love about SAI (working in color, really smooth inking, bucket/fill tools that don't leave empty white lines around inks, brushes that blend while laying down color) and everything I love about Photoshop (filters, warp distortion tools, smooth resizing, lots of file formats, customizable easy to understand workspace layouts) along with a whole bunch of new goodies, like some really nice poseable 3D character models and a brush that automatically draws those difficult frilly lace bits of clothes!
It's $50 and does the job of three programs I'd already had for a long time, which had a total value of about $1050. I got my copies on sale, but still... I always feel kinda guilty about spending money to replace something something that was so expensive, but hey- now I don't have to switch back and forth between three different programs for my comics, and I have even more useful tools now!
By the way, that was NOT a paid advertisement- that's my impression after buying it yesterday and staying up till 2 AM learning it's tricks.